Hematological changes in paraneoplastic syndrome in canines and felines: a literature review

Main Article Content

Pamela Custodio Parra
Julia Cecilia Pirola
Fernanda L. S. B. Varzim

Abstract

Paraneoplastic syndromes (PNS) are a set of alterations resulting from the production of substances by tumors that impact distant areas from the tumor mass or its metastases. These changes occur due to the non-invasive actions of the tumor, such as the release of hormones, peptides, cytokines, or a cross-reaction between normal tissues. The alterations involved in PNS encompass a series of combined effects promoted in other organs, distant from the primary or metastatic tumor origin. The degree of malignancy varies in intensity, and its incidence and diagnosis are poorly studied. The main paraneoplastic syndromes described in small animals include cachexia, fever, neurological, endocrine, cutaneous, and hematological alterations, which will be addressed in the present review. The way as most of these syndromes occur is not yet established or completely understood.

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How to Cite
PARRA, P. C.; PIROLA, J. C.; VARZIM, F. L. S. B. Hematological changes in paraneoplastic syndrome in canines and felines: a literature review. Revista de Educação Continuada em Medicina Veterinária e Zootecnia, v. 22, 31 Jan. 2024.
Section
PATOLOGIA VETERINÁRIA