Study of neurological alterations in dogs submitted to myelography using iopamidol and iohexol as contrast media
Article Sidebar
Main Article Content
Abstract
The objective of this study was to evaluate the side effects of the use of iopamidol and iohexol inmyelography, with and without cerebrospinal fluid (CSF) removal. Twenty-four healthy female dogs, with an average weight of 15 kg, were studied. Methotrimeprazine was used to sedate the dogs; thiopental to induce anesthesia. The subarachnoid space was tapped through the atlanto-occipitalspace with a 30 x 8 needle and a 0.3 ml volume of contrast injected. The dogs were randomly divided into four groups: GI (without CSF removal, iopamidol was used); G2 (with CSF removal,iopamidol was used); G3 (without CSF removal, iohexol was used); G 4 (with CSF removal, iohexol was used). Involuntary limb and head movements, tonic-c1onic contractions, muscular rigidity, vocalization, salivation, mydriasis and seizures were recorded. A66.66% incidence of seizures was found in G1and G2. It was also found that time between the administration of contrast and onset of neurological symptoms was shorter in G1.
Article Details
1. Autores mantém os direitos autorais e concedem à revista o direito de primeira publicação, com o trabalho licenciado sob a Creative Commons Atribuição-NãoComercial-SemDerivações 4.0 Internacional
2. Autores têm autorização para assumir contratos adicionais separadamente, para distribuição não-exclusica da versão do trabalho publicada nesta revista (ex.: publicar em repositório institucional ou como capítulo de livro), com reconhecimento de autoria e publicação inicial nesta revista.
3. Autores têm permissão e são estimulados a publicar e distribuir seu trabalho online (ex.: em repositórios instituicionais ou na sua página pessoal) a qualquer ponto antes ou durante o processo editorial, já que isso pode gerar alterações produtivas, bem como aumentar o impacto e a citação do trabalho publicado (Veja O Efeito do Acesso Livre);