Localization of Leptospira interrogans surface proteins by immunofluorescence

Main Article Content

G. N. R. Timm
J. D. Souza
A. A. Grassmann
A. J. A. Mcbride

Abstract

Leptospirosis is a neglected zoonosis with a worldwide distribution caused by pathogenic spirochetes belonging to the Leptospira genus. Vaccines are the most efficient prophylactic measure for infectious diseases. However, the current vaccine against leptospirosis has numerous disadvantages, such as short-term protection and serovar-related specificity, and, in Brazil, it is only available for animals. Thus, there is a need to develop a new vaccine that can overcome these problems and that can be used in humans. Hence, the discovery of new proteins that are exposed on the bacterial surface, which are promising antigens for a new vaccine, could overcome the shortcomings of bacterin vaccines.

Article Details

How to Cite
TIMM, G. N. R.; SOUZA, J. D.; GRASSMANN, A. A.; MCBRIDE, A. J. A. Localization of Leptospira interrogans surface proteins by immunofluorescence. Revista de Educação Continuada em Medicina Veterinária e Zootecnia, v. 17, n. 2, p. 85-86, 13 Aug. 2019.
Section
CONSENSOS EM LEPTOSPIROSE II